St. Charles Positive Addiction Program is the focus of the school's drug and alcohol education. The program, established in 1983, won national recognition in the spring of 1988 and is being replicated by other schools throughout the United States and world.

During the weeklong program, students in preschool through grade 8 receive instruction concerning drug and alcohol abuse. Junior high students receive intensive education by attending workshops focusing on self-image and relationships with others. Workshops also cover positive addictions or alternatives additions such as jogging, tennis, golf, biking, and biking.  The final day of the program, designated as the Race Day, begins with a liturgy, followed by an assembly with a keynote speaker. The culminating activity of the day is a 3.1 (5K) mile run for sixth, seventh, eighth graders and adults.  Fun runs are for third to fifth graders.  Any student in grades 6 to 8 who are unable to participate in Positive Addiction activities must have a doctor’s note.